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Here we feature our BIOCUTIS® nourishing natural skin care product formulated to reduce the appearance of age spots, melasma (the mask of pregnancy), other hyperpigmentation problems, even skin tone, and nourish aging skin.

This product as all our Biocutis® line is powered by a unique nourishing natural immune serum with powerful antioxidants and complex molecules that fortify the skin cells so that they may orchestrate the normal cycle of healthy skin regeneration.

Laboratory screening of the serum has unveiled that it is a powerful antioxidant substance also packed with enzymes, proteins, peptides, co-enzymes, trace elements (Copper, Zinc, Iron & Calcium) and complex sulfated acidic glyco (sugar) molecules that scientists classify as: glycoproteins, glycosaminoglycans (GAGs) and proteoglycans.

BIO SKIN REJUVENATION has additional natural ingredients that reduce the appearance of excess melanin pigments.

The immune serum supports the important role of our skin as an active organ in our immunity and defense and it is also a sophisticated and very effective topical solution for all types of skin concerns. While safe for all people, regardless of age, gender, color, or skin conditions.

The nourishing skin serum supports the skin cells. We can speculate that well nourished skin cells may then protect the skin from the damaging effects of excessive solar radiation and free radicals, repair damage at the DNA level, and keep skin properly moisturized.

The natural skin rejuvenation serum is also safer, better for you and easier for your body than any clever concoction designed by a pharmacist or a marketing pro.

Skin cells naturally receive nourishment through blood vessels located in the skin. Sometimes the body loses adequate blood flow or proper nutrition due to disease or aging, reducing its ability to nourish the skin and putting it at greater risk for skin breakdown and tearing. It is important for malnourished skin to receive bioavailable nutrition topically to replace lost nourishment.

The skin needs topical support, at all times, particularly in times of distress and this serum provides a complete and balanced nutrition for the skin cells. And well nourished skin cells have a significant positive impact on the optimal functioning of the epidermis and dermis (the cutis).

Through the use of nourishing topical agents, such as our BIOCUTIS serum, the skin can be treated and restored to full function, enabling the skin to be the very effective barrier it is meant to be. A healthy epidermis is flexible yet strong, able to fight off invading organisms and is able to recover and heal after inflammatory and mechanical insults.

BIO SKIN REJUVENATION cream includes a human growth factor peptide, (nonapeptide 1) derived from the melanocyte-stimulating-hormone (MSH) and Rumex extracts that have been shown effective in the reduction of the appearance of unwanted pigmentation allowing control over skin tone and brown and dark spots on the skin.

Visible signs of color reduction in age spots are observed in 3 weeks.


  • The product reduces the appearance of unwanted pigmentation, allowing control over skin tone and brown spots. It helps with pigmented spots such as freckles, solar lentigines (also called liver spots), brown and cafe-au-lait spots, moles, and melasma (localized post-partum darkening of the skin).
  • Nourishes the cells and well nourished cells normally promote cell proliferation and new synthesis of collagen and elastin from within the skin.
  • Powerful enzymatic antioxidant activity by both Superoxide Dismutase (SOD) and Glutathione S-transferase (GSH-T).
  • Protects skin by activity of low molecular antioxidants that have similar effects than those of Vitamin C but without the pitfalls or instability of cosmetics that contain Vitamin C.
  • Replenishes the lipid barrier of the skin.
  • Hydrates the skin and promotes the proliferation of glycosaminoglycans, the molecules that hold water in the skin from within, and firm and strengthen sagging skin.

* Cutis [kyoo-tis] = the true skin, consisting of the dermis and the epidermis.

BIO SKIN REJUVENATION, Powered by BIOCUTIS Serum Nourishes Your Cutis (Epidermis and Dermis) And Has Powerful Antioxidants

The serum is collected from a little mollusk that bubbles this substance onto its skin to protect itself from UV radiation and free radicals.

It is well-known that ultraviolet light induces inflammation of the skin and harmful photochemical reactions therein.

During exposure and as repair of the UV damage takes place, super-oxide (O 2 - ) radicals are formed in the skin. UV irradiation also causes some microvascular damage in the skin. This leads to local hemorrhage and "leakage" of blood cells into the dermis. Iron, from hemoglobin, accumulates in the extra-cellular matrix of the tissue as Fe +2 and Fe +3. It is known that iron catalytically participates in the conversion of superoxide radicals to hydroxyl radicals, a species which is known to be very damaging to tissue.

In addition to their role in UV radiation induced tissue damage, oxygen radicals are known to be capable of reversibly or irreversibly damaging compounds of all biochemical classes. These can include nucleic acids, proteins and free amino acids, lipids, lipoproteins, carbohydrates, and connective tissue macromolecules. These compounds may have an impact on such cell activities as membrane function, metabolism, and gene expression.

Biochemical Mechanisms Of The Immune Serum That Powers Biocutis Skin Care Products

Scientific screening has unveiled the cellular and molecular effects that lead to skin rejuvenation when the serum collected from land snails of the species Cryptomphalus Aspersa or Helix Aspersa, also known as the humble brown garden snail, (and without inflicting any harm to these surprising little creatures), is applied to nourish human skin.

Breakdown of the immune serum has discovered it is a powerful antioxidant substance also packed with enzymes, proteins, peptides, co-enzymes, trace elements (Copper, Zinc, Iron & Calcium) and complex sulfated acidic glyco (sugar) molecules that scientists classify as: glycoproteins, glycosaminoglycans (GAGs) and proteoglycans.

Prestigious Dermatologists Have Done Important Research On The Value Of The Serum

skin regeneration research

skin regeneration research

Read the abstract here: Skin Regeneration Properties of Mollusk Secretion - 2008. Published by the Memorial Sloan-Kettering Cancer Center of New York. And read the abstract of the 2012 scientific research by the Memorial Sloan-Kettering Cancer Center in New York: A secretion of the mollusc Cryptomphalus aspersa (SCA) promotes proliferation, migration and survival of keratinocytes and dermal fibroblasts in vitro".

Studies show the presence of antioxidant activities in the mollusk's secretion. They are enzymatic as superoxide dismutase (SOD), conjugation enzymes as glutathione-S-transferase (GSH-T) and low molecular weight antioxidants related to free radical scavenging activity.

Antioxidant activities of the enzymes Superoxide Dismutase (SOD) and Glutathione S-transferase (GSH-T) found in the secretion confirm studies related to their presence in snail secretions in conditions of post-estivation and also justify a claim that a product made with this ingredient is an excellent antioxidant for the skin.

Snails deal with oxidative stress that takes place during arousal when the pressure of oxygen and oxygen consumption rise rapidly. After they have been estivating or resting inside their shell with the aperture closed by their dry secretion, they increase activities of antioxidant enzymes. Snails display coordinated changes in antioxidant defenses that allow them to deal with oxidative stress that occurs as part of natural cycles of stress/recovery that alter oxygen levels in tissues.

The enzyme superoxide dismutase (SOD), catalyzes the dismutation of superoxide into oxygen and hydrogen peroxide. As such, it is an important antioxidant defense in nearly all cells exposed to oxygen.

Glutathione, an antioxidant, protects cells from toxins such as free radicals.

The Glutathione S-transferase (GST) family of enzymes comprises a long list of cytosolic, mitochondrial, and microsomal proteins which are capable of multiple reactions with a multitude of substrates, both endogenous and xenobiotic. One of its most useful functions is in the detoxification of endogenous compounds.

The secretion has several low molecular antioxidants that have effects similar to other low molecular antioxidants such as Vitamin C.

Enzyme Exfoliation of Denatured And Damaged Skin Proteins

Our skin care creams gently ditch out damaged cells of your skin regularly with the enzymes that are essential components of the serum. And with no trauma, unlike exfoliation with acids or physical abrasion.

Not only will you slough off that dulling, dead, outermost layer of skin that is less than a micron thick, regularly, gently, by the action of dissolving or "digesting" enzymes... but, you will keep the circulation flowing in your body alive, which will rejuvenate your skin.

In healthy young skin an interactive balance exists between these 3 groups of enzymes. This balance is disturbed, when certain enzymes are excessively stimulated or inhibited. The result may be an oily, dry or irritated skin. Epidermal aging processes are activated as well.

During the epidermal aging the horny layer becomes thicker through hyper-keratinization and the living epidermis becomes thinner.

Fruit acids, or alpha hydroxy acids (AHA), have been used until now to regulate these processes. But, AHAs are known to have some side effects as they have to be used in formulations with acidic pH (3.7-4). Stinging or burning sensations can occur.

To avoid this all our products include our complex immune serum with active protease enzymes. The enzymatic complex has a mild keratolytic effect (mild exfoliation, smoothing) and stimulates the turnover of epidermal cells (regenerating activity) leading to a smoother and younger look of the skin.

Our innate immune system cells may need nourishment to help them operate better directly at the site of skin damage for skin repair and to avoid chronic, silent inflammation: inflamm-aging

Our IMMUNE SYSTEM is a complex biological matrix made up of molecules, proteins, cells, and organs that function together to recognize and defend against disease producing bacteria, viruses, fungi, and cells that have undergone malignant transformation.

Your health is dependent on your immune system and its ability to identify and repel your own damaged cells and other invaders.

Our immune system ages with us and its inflammaging responses generate un-repaired cellular damage - the more damage, the earlier you'll likely age... in an unhealthy state up to death.

The cumulative effects of free radical oxidation, physical and psychic stress, heavy metal overload, and vitamin and mineral under nutrition wears it down, increasing our susceptibility to disease.

Mother Nature never anticipated that the immune system she designed for us would be so taxed; here she needs our help.

A Natural Solution That Has Been Before Our Eyes, Unnoticed But With Remarkable Nourishing, Skin Rejuvenation and Immune Support Properties

This serum, for application on the skin, is created by a biological organism with skin tissues and cells that are very much like human skin tissues and cells.

This organism does not have an adaptive immune system but its innate immune system is much more evolved, sophisticated, and faster that the innate immune system of humans.

This is crucial because in both species the "innate" immune system is supposed to react quickly at the site of a local injury, to defend the organism from the effects of solar radiation, pathogens or foreign elements, and to restore the healthy integrity of our body.

This particular species creates a serum or lotion within its immune cells and secretes it onto its skin.

And it also has a fundamental role in the orchestration of the orderly and scar-less regeneration of skin damaged by environmental hazards or insults, and even the regeneration of wounded tissues when such are caused by accidents or by its natural predators.

We believe this naturally occurring serum is a complete and balanced solution for skin care. So complete and balanced that we don't even extract from it any isolates or molecules and set them apart or modify the serum in any way or form, as it is created in the most sophisticated laboratory on Earth: the living cells of a biological organism.

Because of this it has no side effects whatsoever as it is biologically natural, and follows the principle of 'the more whole the ingredient and the less processed it is, the better it is for you'. Also the long-term use of this renewable resource supports sustainable health and beauty of your skin without toxin build-up in the cellular layers of your skin.

All the Ingredients in BIOSKINREJUVENATION: Purified Water, Peg 4 Olivate, Sorbitan Olivate, Helix Aspersa Müller Concentrate, Squalene, Hyaluronic Acid, Glycerin, Rumex Occidentalis Extract, Nonapeptide-1, Phenoxyethanol, Ethylhexylglycerine.

Directions for use: Apply to clean skin, morning and evening, to affected area.

Directions For Routine Skin Care

For mature skin apply BIOSKINREJUVENATION in the morning and evening with your fingertips to reduce the appearance of age spots and have a luminous even skin tone after washing your face with lukewarm water or after cleansing your skin of make up. In the morning wait ten minutes for the beneficial ingredients in this natural treatment to infuse your skin cells and then apply your makeup as usual. It’s that easy.

BIOSKINREJUVENATION is the perfect daily restorative healing, soothing and comforting cream for a blemish-free complexion – even for the most sensitive skin.

Our skin products also provide an intense long-lasting hydration by reinforcing the resistance of the outer skin layer against dehydration.

For more details about the specific skin concerns that each of our products addresses please browse this page further below. You can order our organic natural skin care products from or

Biocutis at Biocutis natural skin care products

Please Note: Our products are not endorsed by the Memorial Sloan-Kettering Cancer Center in New York but their published research validates the skin rejuvenation properties of the immune serum conclusively.

All Natural Skin Care Products

Biocutis at Biocutis healing natural skin care products

Call Us: 1-866-BIO-SKIN or 1-702-947-0567

Customer's Testimonials

I like this cream; seems to be reducing the appearance of scarring and smoothing the skin out. Skin seems to be plumper and more even in tone. It absorbs quickly and leaves the skin moist but not greasy. This is my second order of 2 jars.

Nancy Pickering. PA, USA.

My skin is brighter, clearer, smoother....actually younger looking
I have been using your cream for 5 weeks. My skin is brighter, clearer, smoother....actually younger looking. Yes, I would say it has a glow.....and I'm hooked and just finished ordering more jars.

Deborah Cousins, Bennettsville, SC, US

After just one night's use, my skin already feels smooth and my skin tone is evening out already! It may have worked quick on my so far, because I have oily skin and I am in my early twenties. But I still definitely recommend this to everyone with a problem! And I actually don't use that much when I apply it to my face. It is so cool and light feeling, very comfortable. I just wanted to thank you again and let you know I'll be updating you to tell you how my face has improved! I'm excited! Thanks again.

- N.S. Florida, USA.

I must say so far so good with BIO SKIN REJUVENATION
OK, my face never had a problem as such but your product has helped to soften it further, enhanced my complexion and everyone is telling me I look younger. I am so happy! People are asking me why instead of growing older to reflect my age I am looking as young as a school girl. I have just completed my first jar and I have begun the second. Well I bought your product specifically for some old scars and black spots and my skin already looks brighter and is softer. I must say that I was impressed with your services as well.

Patricia Cortes. Panama .

Excellent product! saw a difference almost immediately. Great for use under make-up. Makes skin look younger, brighter and smoother!!!

Miss Uche Okoli. London

I really love the cream. This is my second order and I feel like it has helped the under-eye area to look younger and some of the acne scars on my face are beginning to fade.

Helen Warren. TX, USA.

I am very satisfied with the product. I use it for reducing the appearance of scars and blemishes. My skin looks younger and the texture has improved a lot.

Carla Martins. Ohio, USA.

Well, I tried it to heal deep burn like places on my face and in the delicate under-eye areas which I had to treat with effudex, a strong medicine to kill pre-cancerous spots. Next, a few small scars (old ones) as well as thin, dry prematurely aging skin wrinkles on face and neck. So far so good. I am noticing a slow and steady improvement and seems my skin is more elastic, thicker and clear. Many thanks!

Sue Bowen, NY, USA.

The main ingredient in the Biocutis line of products is a naturally occurring compound and not a man-made substance so it cannot be patented. This would only be possible if it were an isolate from a natural substance or a man made ingredient achieved through chemical reactions. Thus, by its very nature no one can claim exclusive rights of use granted by a patent of invention.

Why Choose BIOCUTIS®?

  • Nourished the skin cells and they in turn fortify the normal cycle of skin regeneration with cell proliferation and new synthesis of collagen, elastin, and the water holding molecules that warrant proper moisturizing, strength and elasticity
  • Antioxidant - provides protection from the effects of UV radiation and free radicals
  • It is totally compatible with living cells, and thus safe for both babies and octogenarians
  • Its unique skin rejuvenation properties have been confirmed by dermatologists from the Dermatology Service of the New York Memorial Sloan-Kettering Cancer Center, one of the most prestigious in the world
I just completed my second bottle and I am ordering my third. I was extremely skeptical at first because I have tried pretty much everything to clear up break outs, the unsightly looks of old acne scars and signs of aging. Needless to say there was no end to the bottles in my bathroom. Thanks to "Bio Skin Rejuvenation" there has been a definite improvement in my overall skin health. Just recently I had two friends ask me what I have been using because my skin tone has significantly evened up. Thank you for providing a product that actually works!!.
Lori Rouse Seattle, Washington, US

Skin Rejuvenation & Skin Care Products

bio skin rejuvenation for age spots, hyperpigmentation, discoloration and melasma


This cream is the best for the reduction of the appearance of unwanted pigmentation, allowing control over skin tone and brown spots on face and age spots, post inflammatory hyperpigmentation and melasma, (melasma is also known as the mask of pregnancy), while also preventing and reducing the visible signs of premature wrinkles.

Read More →

bio skin care


A pure natural light skin cream for routine skin care and a blemish free complexion. Loosens dead and damaged cells from the outer layer of the skin so that they fall of more easily by the action of enzymes, or the equivalent of a NON-trauma exfoliation, so your skin is not injured to force the normal cycle of skin regeneration, and quickly reveals the youthful skin layers that are being formed beneath the surface...

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night cream


A rich night cream that works while you sleep to reinvigorate all the structures and molecules of your skin, nourish your skin with powerful antioxidants that may scavenge free radicals... for wrinkle proof, energized skin that is deeply hydrated.

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skin treatment serum


Addresses the three major ways in which the visible signs of aging start to show up as we mature: it improves the appearance of the skin so that it looks more thickened although it tends to get thinner, nourishes the cells and then better nourished cells may repair accumulated sun damage, and adds lipids to restore the protective barrier that tends to become depleted of lipids. It also helps to strengthen the appearance of sensitive skin and nourishes the skin cells so that the skin becomes more resilient.

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This website is updated by Alicia Mila a collaborator and affiliate of Andes Natural Skin Care LLC

US & Canada Toll Free: 1-866-BIO-SKIN (866-246-7546) From Outside the USA, please call: 1-702-947-0567

© 2012 Alicia Mila

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The information contained herein has not been evaluated by the Food and Drug Administration and does not constitute medical or pharmaceutical advice and should not be relied upon as a substitute for qualified medical consultation, and is not meant to diagnose, treat, cure or prevent any disease. No such claims are approved by Andes Natural Skin Care, LLC

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